APDA American Parkinson Disease Association
Information & Referral Center

Sweating and Temperature Regulation in PD

Relevant Publications - Downloadable

“Skin and Sweating Problems in Parkinson’s,” by Dr. Ronald Pearce, and Caroline McMahon
Published by Parkinson’s UK, May 2015
This 3-page information sheet explains that sometimes people with Parkinson’s have problems with their skin, and how much or how little they sweat, the symptoms you may experience and what you can do to manage them.


Relevant Online Information

“Excessive Sweating in Parkinson’s Patients,” by Dr. Maria De Leon
Published by defeatparkinsons.com, January 7, 2015
This blog post by neurologist and young onset Parkinson’s patient, Dr. Maria De Leon, explains why we sweat normally, what goes wrong in Parkinson’s disease, what you can do to minimize sweating, and ways to avoid body odor due to excessive sweating.


“Hyperhidrosis Treatment Overview”
Published by the International Hyperhidrosis Society
This is the home page for the International Hyperhidrosis Society, a non-profit organization focused on hyperhidrosis, research, treatment options and clinical trials. Their motto: Know Sweat.


“Skin Changes”
Published by the Parkinson’s Disease Foundation
This short webpage lists symptoms and what you can do for oily, flaky or inflamed skin, dry skin, excessive sweating, and too little perspiration.  Advice is given to be screened regularly for melanomas.


“Skin Problems and Care in Parkinson’s”
Published by the Parkinson Research Foundation
This webpage discusses skin changes common in Parkinson’s disease.  Topics include seborrhea, skin irritation around the mouth from sialorrhea (excessive saliva), hyperhidrosis (drenching sweats), tingling or pain, malignant melanoma, skin patch irritation, pressure sores, fungal infections, and some treatments and preventions for each.


“Skin, Scalp and Sweating”
Published by Parkinson’s Victoria (Australia)
This single webpage has symptoms and management tips for oily skin and scalp, seborrhoeic dermatitis, and too little or too much sweat.


“Sweating (Parkinson’s disease)”
Published by What-When-How, In Depth Tutorials and Information
How the autonomic nervous system regulates many systems, including temperature control, and how Parkinson’s change the body’s temperature regulatory mechanisms leading to symptoms such as hyperhidrosis.


“What is Hyperhidrosis?”
Published by the Hyperhidrosis Support Group(UK)
This website has up-to-date information on affected areas and treatment options for anyone living with hyperhidrosis (excessive sweating), as well as medical staff providing treatment options.


Expert-Level Resources

“Hyperhidrosis in Parkinson’s disease,” by P. Schestatsky, et. al.
Movement Disorders, October 2006
Good summary of prevalence of sweating in a small group of PD patients showing that excessive sweating in PD concurs with decreased activation of sweat glands in the palms of the hands and suggests that axial hyperhidrosis could be a compensatory phenomenon for reduced sympathetic function in the extremities. Registration with PubMed required to read the full article.

“The Relationship between Thermoregulation and REM Sleep Behavior Disorder in Parkinson’s Disease,” by George Zhong, et. al.
PLOS One, August 21, 2013
This open access article provides a thorough description of how thermoregulation occurs and what systems are affected by Parkinson’s disease.

This list updated by Denise Dagan January 2018. This list originally compiled by Steven Russell for the Stanford's Parkinson's Community Outreach Program, February 2017.

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